Endocrine Abstracts

Introduction: Massive anti-SARS-CoV-2 vaccination campaigns have been established as the cornerstone of confronting the current COVID-19 pandemic. Subacute thyroiditis (SAT) comprises an inflammatory process in the thyroid gland, mostly due to viral infections of the upper respiratory tract, although it may rarely occur after vaccine administration. To date, a few cases of SAT related to anti-SARS-CoV-2 vaccines have been reported globally. Hereby, we present the case of a pat...

Introduction: Hyperfunctioning thyroid nodules (toxic adenomas) comprise one of the most common causes of hyperthyroidism and are usually treated with therapeutic radioiodine administration (RAI). Coexistence of such nodules with Graves’ disease (GD) is a rare disorder (Marine-Lenhart syndrome) with a reported prevalence of approximately 2.7–4.1% in GD patients. We present a rare variant of this condition, featuring the case of a patient with hyperfunctioning nodul...

IntroductionThyroid autoimmunity comprises a dynamic entity and may manifest with different forms over the course of time at the same patient, thus causing fluctuations in thyroid functionality. Hereby, we present the case of a patient treated for hypothyroidism of autoimmune etiology, who developed hyperthyroidism accompanied by an excess of thyrotropin receptor autoantibodies (TRAb) and was followed by multiple swings in the thyroid state over an 1.5-y...

Introduction: Primary hyperparathyroidism comprises one of the major causes of hypercalcaemia and is mostly due to solitary parathyroid adenoma. Denosumab is a novel antiresorptive agent for osteoporosis treatment and has been associated with a compensatory increase in PTH levels during the first months after injection, a fact that may interfere in the diagnostic procedures when dealing with concomitant small parathyroid adenomas without standard scintigraphic pattern.<p c...

Background: Levothyroxine (LT4Rx) is one of the most prescribed drugs worldwide the vast majority of patients receive long-term treatment. However, in a recent study of 291 subjects, it was found that 60% were euthyroid 2 months after LT4-Rx discontinuation1.Aim of the study: A prospective clinical cohort follow-up study was carried out. In 688 subjects (82% females) aged 48.01&pm;15.96 (range 17-84years) with 8.59&pm;6.98 years on LT4Rx witho...

Aim: Thyroid cancer comprises the most common endocrine malignancy and a variety of studies have investigated the role of thyroid autoimmunity as an independent risk factor for the manifestation of differentiated thyroid cancer in otherwise benign thyroid disorders. Objective of the current retrospective study is the assessment of any possible correlation between thyroid autoimmunity, in terms of elevated thyroid autoantibodies, and incidental thyroid microcarcinoma (ITC) in n...

Introduction: We retrospectively evaluated all patients with pituitary tumours treated in our department from 1.1.1997–1.11.2014Patients and methods: 215 patients (124 females: 91 males, mean age 50,9 y.) were treated because of pituitary tumours. All patients underwent basal hormonal analysis and testing in order to check for hormonal activity. Pituitary masses were divided into groups concerning their hormonal status and were further classified ac...

Aim: Thyroid cancer comprises the most common endocrine malignancy and a variety of studies have examined the role of TSH as an independent risk factor for the manifestation of differentiated thyroid cancer in otherwise benign thyroid disorders. Objective of the current retrospective study was the assessment of a possible relation between baseline serum TSH and thyroid microcarcinoma in a patient cohort with non-toxic thyroid disorders and without preoperative cytological esta...

Introduction: We retrospectively evaluated all patients with adrenal tumours treated in our Department from 1.1.1999 to 1.10.2013.Patients and methods: 189 patients (110 females: 79 males, mean age of 57.5 years) were treated because of adrenal tumours. All patients underwent hormonal analysis and testing in order to check for hormonal activity. Tumours were classified according to gender, age at diagnosis, tumour localisation and size, as well as benign...

Aim: Thyroid cancer comprises the most common endocrine malignancy and a variety of studies have examined the incidence of microcarcinomas in benign thyroid disorders. Objective of the present retrospective study was the assessment of the possible influence of age and gender parameters in the presence of thyroid microcarcinoma in a patient cohort with non-autonomous thyroid disorders and without cytological establishment of cancer who underwent total thyroidectomy.<p class...